Diclegis
Diclegis (doxylamine succinate and pyridoxine hydrochloride) is a medicine used to treat nausea and vomiting of pregnancy (morning sickness) in women who do not improve with conservative management, such as diet and lifestyle changes. It combines an antihistamine and Vitamin B6 to manage symptoms.
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Product description
Common use
Diclegis is used to treat nausea and vomiting during pregnancy, sometimes called morning sickness. Diclegis is a tablet containing a combination of doxylamine and pyridoxine. Doxylamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Pyridoxine is a form of vitamin B (B6).
Dosage and direction
Use the medicine exactly as directed. Take Diclegis on an empty stomach with a full glass of water. Diclegis is either taken at bedtime, or at bedtime and in the morning. Swallow the capsule or tablet whole and do not crush, chew, or break it. Usual adult dose for nausea or vomiting during pregnancy: 2 tablets orally at bedtime.
Precautions
Tell your doctor if you have ever had: asthma or other breathing disorder; glaucoma, increased pressure inside your eye; blockage in your digestive tract (stomach or intestines); a stomach ulcer; or bladder obstruction or other urination problems.
You should not breast-feed while using Diclegis.
Contraindications
Do not use Diclegis if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.
You should not use this medicine if you are allergic to doxylamine or pyridoxine, or to other antihistamines such as Benadryl or Dramamine.
Possible side effect
Common Diclegis side effects may include: drowsiness.
Drug interaction
Using Diclegis with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety, depression, or seizures.
Missed dose
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Do not take more than 2 tablets in 24 hours.
Overdose
Seek emergency medical attention. Overdose symptoms may include dry mouth, extreme drowsiness or dizziness, confusion, restless feeling, dilated pupils, rapid heartbeats, seizure (convulsions), or muscle pain or weakness with fever and dark colored urine.
Storage
Store at room temperature away from moisture and heat. Keep the pills in their original container, along with the packet or canister of moisture-absorbing preservative. Keep away from children and pets.