Invokana

Common use

Invokana is an oral diabetes medicine that helps control blood sugar levels. Canagliflozin works by helping the kidneys get rid of glucose from your bloodstream. Invokana is used to improve blood sugar control in adults with type 2 diabetes mellitus.
Invokana is also used to lower the risk of death from heart attack, stroke, or heart failure in adults with type 2 diabetes who also have heart disease. Invokana is also used to reduce the risk of end-stage kidney disease and hospitalization or death from heart problems in adults who also have kidney problems caused by type 2 diabetes.

Dosage and direction

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Invokana is usually taken once per day, before the first meal of the day. Usual Adult Dose for Diabetes Type 2: 100 mg orally once a day.

Precautions

To make sure this medicine is safe for you, tell your doctor if you have ever had: heart problems; a diabetic foot ulcer or amputation; circulation problems or nerve problems in your legs or feet; kidney disease; liver disease; bladder infections or other urination problems; a pancreas disorder; if you drink often, or drink large amounts of alcohol; if you are eating less than usual; or if you are on a low salt diet.
Follow your doctor's instructions about using this medicine if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester. You should not use canagliflozin during the second or third trimester of pregnancy. You should not breast-feed while using this medicine.

Contraindications

You should not use Invokana if you are allergic to canagliflozin, or if you have: severe kidney disease (or if you are on dialysis).
Invokana may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.

Possible side effect

Common Invokana side effects may include: genital infections; or urinating more than usual.

Drug interaction

Tell your doctor about all your other medicines, especially: insulin or other oral diabetes medicines; a diuretic or "water pill"; digoxin, digitalis; rifampin; ritonavir; or seizure medication - phenobarbital, phenytoin.

Missed dose

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose

Seek emergency medical attention.

Storage

Store at room temperature away from moisture and heat. Keep away from children and pets.