Nexavar
Nexavar (sorafenib) is a targeted cancer medication used to treat advanced liver cancer (hepatocellular carcinoma), advanced kidney cancer (renal cell carcinoma), and specific types of progressive, radioiodine-resistant thyroid cancer. As a multikinase inhibitor, it stops tumor growth and limits their blood supply.
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Product description
Common use
Nexavar is a cancer medication that interferes with the growth and spread of cancer cells in the body. Nexavar is used to treat liver cancer, thyroid cancer, or kidney cancer.
Dosage and direction
Nexavar is usually taken 2 times per day. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take Nexavar on an empty stomach, at least 1 hour before or 2 hours after eating. Usual adult dose for renal cell carcinoma: 400 mg orally 2 times a day.
Precautions
To make sure Nexavar is safe for you, tell your doctor if you have: heart problems, chest pain, or a heart attack; long QT syndrome (in you or a family member); high blood pressure; an electrolyte imbalance (such as abnormal levels of calcium, magnesium, or potassium in your blood); bleeding problems; or surgery.
Contraindications
You should not use Nexavar if you are allergic to sorafenib, or if you have squamous cell lung cancer and you are being treated with carboplatin and paclitaxel.
Sorafenib can harm an unborn baby or cause birth defects if the mother or the father is using this medicine. If you are a woman, do not use Nexavar if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose. If you are a man, use effective birth control if your sex partner is pregnant or is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
Do not breastfeed while using this medicine, and for at least 2 weeks after your last dose.
Possible side effect
Common Nexavar side effects may include: bleeding; feeling tired; vomiting, diarrhea, nausea, stomach pain; high blood pressure; rash; or weight loss, thinning hair.
Drug interaction
Other drugs may interact with sorafenib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Missed dose
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
Overdose
Seek emergency medical attention.
Storage
Store at room temperature away from moisture and heat. Keep away from children and pets.