Roszet

Common use

Roszet contains two medicines, rosuvastatin and ezetimibe, to lower cholesterol. Roszet is used along with diet in adults with high blood cholesterol levels to reduce low density lipoprotein cholesterol (LDL-C) or bad cholesterol. Roszet is used alone or together with other LDL-lowering medicines in adults with a type of high cholesterol called homozygous familial hypercholesterolemia (HoFH) to reduce LDL-C.

Dosage and direction

Take Roszet exactly as your healthcare provider tells you to take it. Take Roszet 1 time each day, with or without food. It may be easier to remember to take your dose if you do it at the same time every day, such as with breakfast, dinner, or at bedtime. Tablets should be swallowed whole. Do not crush, dissolve, or chew tablets. Keep taking Roszet unless your healthcare provider tells you to stop.

Precautions

Before you start treatment, tell your healthcare provider about all of your medical conditions, including if you: have unexplained muscle aches or weakness; have thyroid problems; have kidney problems; drink more than 2 glasses of alcohol daily or have had liver problems; have diabetes; are pregnant or plan to become pregnant; are 65 years of age or older; are of Asian descent.

Contraindications

Do not take Roszet if you: have liver problems or repeated blood tests showing possible liver problems; are allergic to ezetimibe or rosuvastatin or any of the other ingredients.
Roszet may harm your unborn baby. If you become pregnant, stop treatment and call your healthcare provider right away. Roszet can pass into your breast milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you take Roszet. Do not breastfeed while taking Roszet.

Possible side effect

The most common side effects include: headache; weakness; diarrhea; dizziness; pain (back, hands, legs); nausea; constipation; joint pain; stomach pain; muscle aches and pains; common cold and flu; runny nose and sore throat; tiredness.

Drug interaction

If you also take cholestyramine, colesevelam, or colestipol: Take your Roszet dose 2 hours before or 4 hours after you take the other medicine.
Tell your doctor about all your other medicines. Some drugs can increase the risk of serious muscle problems when used with ezetimibe and rosuvastatin, especially: colchicine, cyclosporine; antifungal medication - fluconazole, itraconazole, ketoconazole; a blood thinner - warfarin, Coumadin, Jantoven; cancer medicine - darolutamide, regoragenib; other cholesterol medications - fenofibrate, fenofibric acid, gemfibrozil, niacin, nicotinic acid; hepatitis C medication that contains - dasabuvir, elbasvir, glecaprevir, grazoprevir, ledipasvir, ombitasvir, paritaprevir, pibrentasvir, sofosbuvir, velpatasvir, or voxilaprevir; or HIV/AIDS medication - atazanavir, fosamprenavir, lopinavir, ritonavir, simeprevir, tipranavir.

Missed dose

If you miss a dose, do not take an extra dose. Take the next dose at the usual time. Do not take 2 doses of Roszet within 12 hours of each other.

Overdose

If you take too much or overdose go to the nearest hospital emergency room right away.

Storage

Store Roszet at room temperature between 68°F to 77°F (20°C to 25°C). Protect Roszet from moisture or humidity. Keep away from children and pets.