Tecfidera
Tecfidera (dimethyl fumarate) is an oral medication used to treat relapsing forms of multiple sclerosis (MS) in adults, including clinically isolated syndrome (CIS), relapsing-remitting disease (RRMS), and active secondary progressive disease. It works as a disease-modifying therapy (DMT) to reduce inflammation, decrease the number of flare-ups, and slow the progression of physical disability.
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Product description
Common use
Tecfidera is used to treat relapsing forms of multiple sclerosis (MS) to help you have fewer relapses, delay the progression of disability, and slow brain lesion development. Tecfidera may help delay the progression of relapsing forms of multiple sclerosis (MS).
Dosage and direction
Take Tecfidera exactly as prescribed by your doctor. You may take Tecfidera with or without food. Taking the medicine with food may help prevent flushing (sudden warmth, redness, or tingly feeling). Swallow the capsule whole, and do not crush, chew, break, or open it. Usual Adult Dose for Multiple Sclerosis: 120 mg orally twice a day for 7 days; Maintenance dose: 240 mg orally twice a day.
Precautions
To make sure this medication is safe for you, tell your doctor if you have ever had: an active infection; or low white blood cell (WBC) counts.
Tell your doctor if you are pregnant or plan to become pregnant, as it is not known if Tecfidera will harm your unborn baby. Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if Tecfidera passes into your breast milk. You and your doctor should decide if you will take this medicine or breastfeed.
Contraindications
You should not use Tecfidera if you have had a severe allergic reaction to dimethyl fumarate, diroximel fumarate (Vumerity), or any of the inactive ingredients contained in this medication.
This medicine may cause a serious viral infection of the brain that can lead to disability or death. Call your doctor right away if you have any change in your mental state, decreased vision, weakness on one side of your body, or problems with speech or walking. These symptoms may start gradually and get worse quickly.
Possible side effect
Common Tecfidera side effects include: stomach pain, indigestion, nausea, vomiting, diarrhea, redness, rash, itching, or flushing (sudden warmth, redness, or tingly feeling).
Drug interaction
Other drugs may interact with dimethyl fumarate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Missed dose
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Overdose
Seek emergency medical attention.
Storage
Store this medicine in the original container at room temperature, away from moisture, heat, and light. Keep away from children and pets.