Tribenzor

Common use

Tribenzor is used to treat high blood pressure (hypertension). Tribenzor contains a combination of amlodipine, hydrochlorothiazide, and olmesartan. Amlodipine is a calcium channel blocker that relaxes (widens) blood vessels and improves blood flow. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Olmesartan is an angiotensin II receptor antagonist (sometimes called an ARB) that keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Dosage and direction

Follow all directions on your prescription label and read all medication guides or instruction sheets. You may take Tribenzor with or without food. Usual adult dose for Hypertension: Amlodipine 5 to 10 mg, Hydrochlorothiazide 12.5 to 25 mg, Olmesartan 20 to 40 mg orally once a day.
Your chest pain may become worse when you first start taking this medicine or when your dose is increased. Call your doctor if your chest pain is severe or ongoing. You can easily become dehydrated while taking Tribenzor. Drink plenty of water each day. Your blood pressure will need to be checked often.

Precautions

To make sure Tribenzor is safe for you, tell your doctor if you have ever had: kidney disease; liver disease; heart disease; an electrolyte imbalance (such as high levels of calcium, or low levels of potassium or magnesium in your blood); low blood pressure; glaucoma; lupus; gout; diabetes; or a penicillin allergy.
If you have diabetes, do not use Tribenzor together with any medication that contains aliskiren (a blood pressure medicine). You may also need to avoid taking Tribenzor with aliskiren if you have kidney disease.

Contraindications

You should not use Tribenzor if you are allergic to amlodipine, hydrochlorothiazide, or olmesartan, or: if you are allergic to any sulfa drug; or if you are unable to urinate.
Do not use Tribenzor if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Olmesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. You should not breastfeed while using Tribenzor.

Possible side effect

Common Tribenzor side effects may include: dizziness; headache, tired feeling; swelling in your hands or feet; nausea, diarrhea; runny or stuffy nose, sore throat; muscle spasms; swollen joints; or painful urination.

Drug interaction

Tell your doctor about all your current medicines. Many drugs can affect Tribenzor, especially: another a diuretic or "water pill"; any other blood pressure medicines; insulin or oral diabetes medicine; steroid medicine; vitamin or mineral supplements that contain potassium; a sedative or opioid medicine; cholesterol-lowering medicine; an antibiotic, antifungal, or antiviral medicine; or NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), and others.

Missed dose

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose

Seek emergency medical attention.

Storage

Store Tribenzor at room temperature away from moisture and heat. Keep away from children and pets.